Agreement with a collaborating physician who also has admitting and clinical privileges at the same participating hospital. This physician must be a network participating provider. The Hospital Admitting Arrangement Form must list at least one Community Health Plan participating provider who is willing to provide inpatient coverage until the applicant has been fully approved for hospital privileges. In the event a provider does not have hospital admitting privileges and practices in a specialty, which is required to maintain admitting privileges under this criterion, the Community Health Plan must obtain documentation of applicant's inpatient coverage arrangement to assure continuity of care for applicant's hospitalized patients. The Hospital Admitting Arrangement Form must list at least one Community Health Plan participating provider who is willing to provide admitting and inpatient coverage. If the provider 's hospital inpatient arrangement is with a nonparticipating provider , the Credentials Specialist will verify that there are no current Medicare or Medicaid sanctions and that the professional license of the covering provider is active and in good standing. Hospital affiliation will be verified by attestation of the provider; or in writing, by phone or electronically with the hospital medical staff office. This verification is documented in the provider's credentialing file. If the application process for hospital privileges is not completed or the applicant has been denied hospital privileges by the hospital board, the provider is required to contact Community Health Plan's CMO or delegate Medical Director ; immediately. The applicant must report hospital adverse actions on privileges or membership to the Community Health Plan. Failure to report any adverse action decision on hospital membership or hospital privileges within 30 days of the action can result in termination of the provider from the Community Health Plan. Adverse actions on hospital membership or privileges must include documented follow-up by the Credentialing Specialist. Such actions include denial, revocation, suspension, restriction, reduction, limitation, sanction, probation, monitoring, non-renewal, voluntarily relinquishment, withdrawal or failure to proceed with an application or reapplication for any reason. Providers who relinquish their medical staff membership or privileges to avoid a peer review decision or action will generally not be considered for inclusion in Community Health Plan's network. Exceptions: A. Providers in some specialties are not required to have, or are not eligible to obtain, admitting privileges. These specialties may include, but are not limited to, anesthesiology, pathology, dermatology, psychiatry, radiology, urgent care and emergency medicine. Additional provider types that may not be eligible to obtain admitting privileges include advanced registered nurse practitioners ARNPs ; , midwives LM, CNM ; , certified physician assistants PA-Cs ; and chiropractors DCs.
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Multilinear PLS Analysis with Application to 3D QSAR 5.1 5.2 5.3 Introduction .93 Theory .95 Results .99 Discussion .103 Conclusions.106 Matlab Code for Regression Coefficients .106 References.108.
20. Draznin B, Sussman KE, Eckel RH, Kao M, Yost T, Sherman NA: Possible role of cytosolic free Ca concentrations in mediating insulin resistance of obesity and hyperinsulinemia. J Clin Invest 82: 1848 1852, Tongyai S, Rayssiguier Y, Motta C, Gueux E, Maurois P, Heaton FW: Mechanism of increased erythrocyte membrane fluidity during magnesium deficiency in weanling rats. J Physiol 257: C270 C276, 1989 22. Suarez A, Pulido N, Casla A, Casanova B, Arrieta FJ, Rovira A: Impaired tyrosinekinase activity of muscle insulin receptors from hypomagnesaemic rats. Diabetologia 38: 12621270, 1995 Goran MI: Measurement issues related to studies of childhood obesity: assessment of body composition, body fat distribution, physical activity, and food intake. Pediatrics 101: 505518, 1998 Livingstone MB, Prentice AM, Coward WA, Strain JJ, Black AE, Davies PS, Stewart CM, McKenna PG, Whitehead RG: Validation of estimates of energy intake by weighed dietary record and diet history in children and adolescents. J Clin Nutr 56: 29 35, Suitor CW, Gleason PM: Using dietary reference intake-based methods to estimate the prevalence of inadequate nutrient intake among school-aged children. J Diet Assoc 102: 530 536, Brink EJ, Beynen AC: Nutrition and magnesium absorption: a review. Prog Food Nutr Sci 16: 125162, 1992 Coudray C, Demigne C, Rayssiguier Y: Effects of dietary fibers on magnesium absorption in animals and humans. J Nutr 133: 1 4, Humphries S, Kushner H, Falkner B: Low dietary magnesium is associated with insulin resistance in a sample of young, non-diabetic black Americans. J Hypertens 12: 747756, 1999 Song Y, Manson JE, Buring JE, Liu S: Dietary magnesium intake in relation to plasma insulin levels and risk of type 2 diabetes in women. Diabetes Care 27: 59 65, Meyer KA, Kushi LH, Jacobs DR Jr, Slavin J, Sellers TA, Folsom AR: Carbohydrates, dietary fiber, and incident type 2 diabetes in older women. J Clin Nutr 71: 921 930, Paolisso G, Sgambato S, Pizza G, Passariello N, Varricchio M, D'Onofrio F: Improved insulin response and action by chronic magnesium administration in aged NIDDM subjects. Diabetes Care 12: 265269, 1989 Guerrero-Romero F, Tamez-Perez HE, Gonzalez-Gonzalez G, Salinas-Martinez AM, Montes-Villarreal J, Trevino-Ortiz.
GALANIN-INDUCED CONTRACTION OF RAT JEJUNUM ileum smooth muscle cells. J. Physiol. Lond. ; 458: 475486, 1992. Botella, A., M. Delvaux, J. Fioramonti, J. Frexinos, and L. Bueno. Galanin contracts and relaxes guinea pig and canine intestinal smooth muscle cells through distinct receptors. Gastroenterology 108: 311, 1995. Courtice, G. P., J. R. S. Hales, and E. K. Potter. Selective regional vasoconstriction underlying pressor effects of galanin in anaesthetized possums compared with cats. J. Physiol. Lond. ; 481: 439445, 1994. Delvaux, M., A. Botella, J. Fioramonti, J. Frexinos, and L. Bueno. Galanin induces contraction of smooth muscle from pig ileum by a direct myogenic effect. Regul. Pept. 32: 369374, 1991. Feher, E., and G. Burnstock. Galanin-like immunoreactive nerve elements in the small intestine of the rat. An electron microscopic immunocytochemical study. Neurosci. Lett. 92: 137 142, Fish, R. D., G. Sperti, W. S. Colucci, and D. E. Clapham. Phorbol ester increases the dihydropyridine-sensitive calcium conductance in a vascular smooth muscle cell line. Circ. Res. 62: 10491054, 1988. Fontaine, J., and P. Lebrun. Galanin: Ca2 -dependent contractile effects on isolated mouse distal colon. Eur. J. Pharmacol. 164: 583586, 1989. Galizzi, J.-P., J. Qar, M. Fosset, C. Van Renterghem, and M. Lazdunski. Regulation of calcium channels in aortic muscle cells by protein kinase C activators diacylglycerol and phorbol esters ; and by peptides vasopressin and bombesin ; that stimulate phosphoinositide breakdown. J. Biol. Chem. 262: 6947 6950, Gerthoffer, W. T. Calcium dependence of myosin phosphorylation and airway smooth muscle contraction and relaxation. Am. J. Physiol. 250 Cell Physiol. 19 ; : C597C604, 1986. Gerthoffer, W. T. Dissociation of myosin phosphorylation and active tension during muscarinic stimulation of tracheal smooth muscle. J. Pharmacol. Exp. Ther. 240: 815, 1987. Gonda, T., E. E. Daniel, T. J. McDonald, J. E. T. Fox, B. D. Brooks, and M. Oki. Distribution and function of enteric GAL-IR nerves in dogs: comparison with VIP. Am. J. Physiol. 256 Gastrointest. Liver Physiol. 19 ; : G884G896, 1989. Gong, M. C., M. T. Kinter, A. V. Somlyo, and A. P. Somlyo. Arachidonic acid and diacylglycerol release associated with inhibition of myosin light chain dephosphorylation in rabbit smooth muscle. J. Physiol. Lond. ; 486: 113122, 1995. Gu, Z.-F., T. K. Pradhan, D. H. Coy, and R. T. Jensen. Galanin-induced relaxation in gastric smooth muscle cells is mediated by cyclic AMP. Peptides 15: 14251430, 1994. Gu, Z.-F., T. K. Pradhan, D. H. Coy, and R. T. Jensen. Smooth muscle cells from guinea pig stomach possess high-affinity galanin receptors that mediate relaxation. Am. J. Physiol. 266 Gastrointest. Liver Physiol. 29 ; : G839G845, 1994. Gu, Z.-F., T. K. Pradhan, D. H. Coy, and R. T. Jensen. Interaction of galanin fragments with galanin receptors on isolated smooth muscle cells from guinea pig stomach: identification of a novel galanin receptor subtype. J. Pharmacol. Exp. Ther. 272: 371378, 1995. Gu, Z.-F., W. J. Rossowski, D. H. Coy, T. K. Pradhan, and R. T. Jensen. Chimeric galanin analogs that function as antagonists in the CNS are full agonists in gastrointestinal smooth muscle. J. Pharmacol. Exp. Ther. 266: 912918, 1993. Kato, H., T. Hayashi, Y. Koshini, Y. Kutsumi, T. Nakai, and S. Miyabo. Glucocorticoids increase Ca2 influx through dihydropyridine-sensitive channels linked to activation of protein kinase C in vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 188: 934941, 1992. Kitazawa, T., B. D. Gaylinn, G. H. Denney, and A. P. Somlyo. G-protein-mediated Ca2 sensitization of smooth muscle contraction through myosin light chain phosphorylation. J. Biol. Chem. 266: 17081715, 1991.
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PATIENTS One hundred seventy patients received study medication, 87 for amoxicillin-clavulanate every 12 hours 12-hour group ; and 83 for every 8 hours 8-hour group ; . A total of 134 patients 78.8% ; were evaluated at the end of therapy and completed the study according to protocol. Patient characteristics are given in Table 1. No significant differences were detected P .05 ; with respect to any of the baseline characteristics. Compliance with the antibiotic regimen 80% and 120% of doses taken ; was similar for the 12hour and 8-hour groups 92% [80 87] and 96% [80 83] and antabuse.
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E- Subtitles: Emotional Subtitles as a Technology to Assist the Deaf and Hearing-Impaired when Learning from Television and Film 464 James Ohene-Djan and Rachel Shipsey Effect of Creative Lesson by using Cyber Theater Gallery .467 Hiroshi Matsuda and Yoshiaki Shindo Effect of Feedback during Lecture Style Delivery both in a Face-to-Face Classroom & During a Distance Education Television Session in a Developing Country like Bangladesh without the Use of Internet .469 Yousuf M. Islam, Zillur Rahman, Shafiq Shamsur Razzaq, Md. Abu Sayed, and Shakib Zaman Effective Analysis and Design of Computer-Supported Learning System.472 David Dez Cebollero, Camino Fernndez Llamas, and Juan Manuel Dodero Effectiveness of Collaborative e-Test Construction .474 Pokpong Songmuang, Maomi Ueno, and Toshio Okamoto eLearning, Interactive Hypermedia, Neuroscience and Digital Learning Module Creation.477 Javed Alam Elkar-CM: A Multilingual Collaborative Concept Map Editor .482 Cristbal Arellano, Urko Rueda, Ianire Niebla, Mikel Larraaga, Ana Arruarte, and Jon A. Elorriaga Employing Object-Oriented Design Principles in the Design of Learning Objects in a Software Engineering Course .484 Permanand Mohan, Sandra Bucarey A, and Ben Daniel Enhancing Lifelong Competence Development and Management Systems with Social Network-based Concepts and Tools .487 Alicia M. Cheak, Albert A. Angehrn, and Peter Sloep Enhancing Web Supported Learning by Adding a Management Layer to SCORM Compliant LMSs.489 Carlos Sousa Pinto and Fernando M.S. Ramos E-portfolios Along the Lifelong Learning Cycle: Differences between Use, Pedagogy and Context.491 Christopher Murray and Neil Currant E-Portfolios and Cross-Cultural Assessment.494 Johannes C Cronj Estimating the Gaze Point of a Student in a Driving Simulator .497 Wim Fikkert, Dirk Heylen, Betsy van Dijk, Anton Nijholt, Jorrit Kuipers, and Arnd Brugman Evaluating Real-time Online Research Data RORD ; and Verbatim Quotient Detection VQD ; : Low Inference Tools to Monitor Outcomes of Unconstrained Authentic Internet Research.502 Nasiroh Omar, Colin Higgins, Colin Harrison, and Diego Campo Millan Evaluation of a Queuing Theory and Systems Modeling Course Based on UML.507 Athanasios Perdos, Alexander Chatzigeorgiou, and George Stephanides Evaluation of Team Activities in an Engineering Design Course with an E-Learning System.510 Kazuya Takemata, Masakatsu Matsuishi, Shigeo Matsumoto, Tetsurou Furukawa, Taketo Yamakawa, and Akiyuki Minamide Evolution of the Teacher Roles and Figures in E-learning Environments.512 M. Elena Rodrguez, Montse Serra, Jordi Cabot, and Isabel Guitart.
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Background: Current, live virus vaccines for smallpox have unacceptable side effects including inadvertent inoculation and mortality. Here, we present study on the development of a safe, killed-virus vaccine. We used nanoemulsion, a soy-oil based antimicrobial with virucidal activity toward Vaccinia Virus VV ; , as an adjuvant for a killed virus nasal vaccine. Methods: For intranasal administration a NE approved for human use was mixed with 1 x 105 pfu of VV Western Reserve WR ; serotype. The development of immunity was evaluated by systemic, mucosal, neutralizing antibody and cellular responses. Protective immunity was tested in challenge with a lethal dose of VV. Results: Incubation with NE resulted in virus inactivation and documented absence of viral replication in animals after vaccination. Anti-VV mucosal IgA and serum IgG were detected after a single intranasal dose of VV NE and the immune response was optimized with booster administrations. High titers of VV neutralizing antibodies were detected in mice immunized with NE-killed virus. All animals vaccinated with VV NE were protected against lethal challenge with live virus. No protective immunity was observed in animals vaccinated with formalinkilled virus. Virus-specific INF-g production in splenocytes indicated Th1 polarization of immunity. The complex mechanism of NE adjuvant involves inactivation of the virus through removal of viral envelope proteins, triggering the uptake of the proteins and activation of the antigen presenting cells in the mucosa. Conclusions: VV inactivated by NE is immunogenic and can serve as an antigen in killed-virus vaccine for smallpox. The NE is necessary for the development of a robust protective mucosal and systemic immunity. References: 1. Myc A, Kukowska-Latallo JF, Bielinska AU, Cao P, Myc PP, Janczak K, Sturm TR, Grabinski MS, Landers JJ, Young K, Chang J and apidra.
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2, 762, 000 have exercise prices between .10 and .89 with a weighted average exercise price of .91 and a weighted average remaining contractual life of 7.01 years. Of these 2, 762, 000 options, 1, 399, 000 are exercisable; their weighted average exercise price is .29. 2, 811, 000 options have exercise prices between .00 and .87 with a weighted average exercise price of .83 and a weighted average remaining contractual life of 5.52 years. Of these 2, 811, 000 options, 2, 372, 000 are exercisable; their weighted average exercise price is .87. 3, 000, 000 options have exercise prices between .25 and .44 with a weighted average exercise price of .54 and a weighted average remaining contractual life of 7.60 years. Of these 3, 000, 000 options, 1, 170, 000 are exercisable; their weighted average exercise price is .64 and apomorphine.
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